The 2025 NFL playoffs opens with two AFC matchups on Saturday with the Houston Texans hosting the Los Angeles Chargers at 4:30 p.m. ET, followed by the Baltimore Ravens hosting the Pittsburgh Steelers at 8 p.m. ET on Wild Card Weekend. The opening round of the NFL playoffs 2025 has expanded into a three-day event, creating more opportunities for daily Fantasy football players to form NFL DFS lineups from smaller NFL DFS player pools in different formats. Although there are only four teams to pick from, Saturday still has intriguing options for NFL DFS picks such as Lamar Jackson, Derrick Henry, Justin Herbert, J.K. Dobbins, Nico Collins, C.J. Stroud and Russell Wilson. Which top players should be featured in your NFL DFS strategy and who are some under-the-radar NFL DFS sleepers to consider for NFL DFS lineups? Before locking in any NFL DFS picks for Wild Card Weekend Saturday for Chargers vs. Texans and Steelers vs. Ravens on sites like DraftKings and FanDuel, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor.
Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings’ NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks on sites like DraftKings and FanDuel.
Kaylor has hit on epic NFL DFS picks for SportsLine members. He was all over slate-breaking performances like Travis Kelce’s (7-25-4), Kirk Cousins (460-4), T.J. Hockenson’s (13-109-2), Ja’Marr Chase’s (15-1923), D.J. Moore’s (8-230-3), and De’Von Anchane (233 total yards, four TDs). This season, some of Kaylor’s top picks include Green Bay wide receiver Jayden Reed (4-138-1, 33-1) and James Cook (78-2). Anyone who followed his picks on sites like DraftKings and FanDuel could be way up.
Now, Kaylor has turned his attention to Wild Card Weekend on Saturday in the 2025 NFL playoffs and locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.
Top NFL DFS picks for Texans vs. Chargers and Ravens vs. Steelers on Saturday
One of Kaylor’s top NFL DFS picks for Saturday Wild Card Weekend is Ravens running back Derrick Henry ($8,200 on DraftKings and $9,800 on FanDuel). Henry may be 31 years old, but he still runs as hard as a rookie looking to prove himself in the league. He finished the regular season strong with 138 rushing yards and two touchdowns on 20 carries for 6.9 yards per rush against the Browns last week. Henry rushed for 1,921 yards this season, the second-most of his nine-year NFL career, as he averaged 113 rushing yards per game.
Henry recently rushed for 162 yards on 24 carries (6.8 yards per rush) while adding two receptions for 27 yards in Week 16 against the Steelers. He had 65 yards and a touchdown on just 13 carries in Baltimore’s first matchup against Pittsburgh and after finishing as the RB4 in Fantasy football this season, Kaylor views Henry as a strong play for Saturday NFL DFS lineups. See who else to roster here.
Kaylor’s Saturday Wild Card Weekend NFL DFS strategy also includes rostering Chargers wide receiver Ladd McConkey ($6,800 on DraftKings and $7,500 on FanDuel). The No. 34 overall pick in the 2024 NFL Draft had a slower start to his NFL career than some of the other top pass-catchers in his draft class, but he finished with as strong of a finish as any receiver in the league. McConkey had fewer than 50 yards in five of his first six contests, but he finished with at least 80 yards in six of his last seven games. He had more than 90 yards in each of his last two games, including five receptions for 95 yards last week against the Raiders.
The rookie led Los Angeles in receptions (82), receiving yards (1,149) and targets (112). He was second on the team in receiving touchdowns (seven) and his 15 plays of more than 20 yards also led the Chargers. McConkey’s chemistry with Justin Herbert strengthened as the season progressed and the Chargers enter the postseason scoring at least 34 points in three straight games. See who else Kaylor likes right here.
How to set Saturday NFL DFS lineups, player pools
Kaylor is also targeting another undervalued player who could explode for huge numbers for Wild Card Weekend Saturday. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor’s NFL DFS picks, at SportsLine.
So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Chargers vs. Texans and Steelers vs. Raves on Saturday, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from an NFL DFS expert who won a prestigious Millionaire Maker tournament, and find out.
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