Broncos vs. Bills odds, picks, spread, how to watch, stream: Model shares 2025 NFL Wild Card predictions

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Two of the NFL’s most exciting teams will meet on Wild Card Weekend as Josh Allen and the Buffalo Bills host Bo Nix and the Denver Broncos on Sunday on Paramount+. The Bills locked up the No. 2 seed in the AFC and had won 10 of 11 games ahead of the NFL Playoffs before falling 23-16 to the New England Patriots in Week 18 with most of their starters resting. Meanwhile, the Broncos had to battle to lock up a spot in the NFL playoff bracket, finally pushing through with a 38-0 win against the Patrick Mahomes-less Kansas City Chiefs in the regular-season finale. You can stream Saturday’s game live on Paramount+, which you can now try free for the first seven days when you sign up here.

Kickoff from Highmark Stadium in Buffalo is 1 p.m. ET. The Bills are 8.5-point favorites in the latest Bills vs. Broncos odds via SportsLine consensus, and the over/under for total points scored is 47.5. Sunday’s game will be streamed live on Paramount+ with their must-have Paramount+ with SHOWTIME plan, which you can now get on a 7-day free trial.

Paramount+ is the only place to watch every minute of every NFL on CBS game this season. A subscription also gives you access to other sports content including the UEFA Champions League and Europa League, NWSL, Serie A, and countless movies and shows. You can now get a free 7-day trial, so sign up right here

How to watch Broncos vs. Bills

  • Bills vs. Broncos date: Sunday, Jan. 12
  • Bills vs. Broncos time: 1 p.m. ET
  • Bills vs. Broncos TV channel: CBS 
  • Bills vs. Broncos streaming: Paramount+ 

NFL playoff picks for Broncos vs. Bills

Before tuning into Sunday’s Bills vs. Broncos Wild Card Weekend game, you need to see the NFL picks from SportsLine’s advanced computer model. The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2025 NFL playoffs on a 31-14 betting hot streak on top-rated NFL picks this year, a stunning 69% success rate. Longer term, it is on a 211-142 roll on top-rated NFL picks that dates back to the 2017 season and a 65-35 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone following at sportsbooks and on betting apps could have seen strong returns.

For Bills vs. Broncos, the model is backing Buffalo to cover the spread in well over 50% of simulations. Denver did well against the spread this season, going 12-5-0 ATS as they exceeded expectations for Bo Nix’s rookie campaign. However, they were also 4-5 straight as a road team this season, while the Bills were a perfect 8-0 at Highmark Stadium.

The Broncos’ passing defense ranked 19th in the NFL during the regular season, allowing 220.7 average points per game and 22 touchdowns through the air. They will be heavily challenged in containing Allen, who threw for 3,731 yards while running for another 531 yards and scoring 40 touchdowns overall. The Bills overall defense ranked 17th overall in the league, but is expected to put plenty of pressure on Nix in the Oregon product’s playoff debut. You may be able to stream the game here.

How to watch, live stream the NFL on CBS

Now that you know what to pick, get ready to watch your live local NFL on CBS games and Broncos vs. Bills on Paramount+ on any device you want. Don’t forget you can now try Paramount+ free for the first week.

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