MLB Opening Day 2025: Schedule, matchups, previews and more

The major league regular season kicked off in Japan this week — meaning MLB Opening Week is just around the corner.

On March 27, 28 of 30 MLB teams will play in 14 Opening Day games. ESPN will broadcast two of them: the first of the day, Brewers-Yankees, in the late afternoon and a primetime matchup between the reigning champion Dodgers and the Tigers. Meanwhile, the Rays and Rockies will play their first game the following day, March 28.

Thirty of the best pitchers across the majors will take the mound, including 22 All-Stars, four pitchers who will be debuting for new clubs and one who will become the fastest top overall pick to take the mound in a season opener.

What are the most important things to know from the offseason going into the 162-game marathon that is the 2025 season? What are the most exciting matchups on March 27? What are some storylines to watch?

We have you covered on everything you need to be prepared for Opening Day, from season previews and analysis to the schedule.

Opening Day schedule

Thursday, March 27

(All times ET)

The pitching matchup: Freddy Peralta vs. Carlos Rodón


The pitching matchup: Zach Eflin vs. Jose Berrios


The pitching matchup: Garrett Crochet vs. Nathan Eovaldi


The pitching matchup: Zack Wheeler vs. MacKenzie Gore


The pitching matchup: TBD vs. Cole Ragans


The pitching matchup: Clay Holmes vs. Framber Valdez


The pitching matchup: Logan Webb vs. Hunter Greene


The pitching matchup: Chris Sale vs. Michael King


The pitching matchup: Yusei Kikuchi vs. Sean Burke


The pitching matchup: Paul Skenes vs. Sandy Alcantara


The pitching matchup: Pablo Lopez vs. Sonny Gray


The pitching matchup: Tarik Skubal vs. TBD


The pitching matchup: TBD vs. TBD


The pitching matchup: Luis Severino vs. Logan Gilbert


Friday, March 28

The pitching matchup: Kyle Freeland vs. Shane McClanahan

2025 season guides

Fantasy baseball cheat sheet

Jeff Passan’s 2025 season preview: Predictions, inside intel and breakout stars for all 30 teams

Which young players will rock 2025? Ranking the top prospects in MLB’s Spring Breakout

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