Purdue vs. Indiana odds, prediction, line: 2025 college basketball picks, Jan. 31 best bets from proven model

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The No. 10 Purdue Boilermakers (16-5, 8-2 Big Ten) will try to maintain their winning ways when they host the Indiana Hoosiers (14-7, 5-5) on Friday night. Purdue has won eight of its last nine games, including a 91-64 win over then-No. 21 Michigan last Friday. The Boilermakers are in second place in the conference standings, trailing unbeaten Michigan State (9-0) in league play. Indiana has lost four of its last five games, falling to Maryland in a 79-78 final on Sunday.  

Tipoff is set for 8 p.m. ET on Friday at Mackey Arena. Purdue is favored by 12 points in the latest Purdue vs. Indiana odds, while the over/under is 146 points, per SportsLine consensus. Before entering any Indiana vs. Purdue picks, you’ll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 13 of the 2024-25 season on an 202-142 betting roll (+2468) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has set its sights on Purdue vs. Indiana. You can head to SportsLine to see its picks. Here are several college basketball betting lines for the game:

  • Purdue vs. Indiana spread: Purdue -12
  • Purdue vs. Indiana over/under: 146 points
  • Purdue vs. Indiana money line: Purdue -900, Indiana +586
  • Purdue vs. Indiana picks: See picks here
  • Purdue vs. Indiana streaming: FuboTV (Try for free)

Why Purdue can cover

Purdue has won eight of its last nine games, and it has dominated this head-to-head series in recent years. The Boilermakers have won 15 of the last 19 meetings, winning the two games last season by a combined 41 points. They are coming off one of their best performances of the campaign, crushing then-No. 21 Michigan in a 91-64 final. 

Junior guard Braden Smith nearly posted a triple-double, finishing with 24 points, 10 assists and seven rebounds. Four starters finished in double figures for Purdue, including a 15-point effort from junior forward Trey Kaufman-Renn. He leads the team with 18.1 points and 6.3 rebounds per game, while Smith is averaging 15.4 points and 8.9 assists. See which team to pick here. 

Why Indiana can cover

Indiana beat Ohio State in overtime two weeks ago, pulling off the outright upset as an 8-point underdog. Senior forward Luke Goode had 23 points and knocked down four 3-pointers, including a massive triple with one minute remaining in overtime. Senior center Oumar Ballo posted a double-double with 21 points and 15 rebounds, shooting 8 of 14 from the floor.

The Hoosiers have lost their two games since then, but both of those setbacks came by single digits. They were 2.5-point underdogs in their 79-78 loss to Maryland on Sunday, as Ballo had another double-double with 14 points and 10 rebounds. Indiana has covered the spread in four of its last six games against Purdue. See which team to pick here. 

How to make Purdue vs. Indiana picks

The model has simulated Indiana vs. Purdue 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread is the better value. You can only see the pick at SportsLine.

So who wins Purdue vs. Indiana, and which side of the spread is the better value? Visit SportsLine now to see which side of the Purdue vs. Indiana spread you need to jump on, all from the model on an 202-142 roll on top-rated college basketball picks, and find out.

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