Week 1 of the 2025 college football season will feature four prominent games between the ACC and SEC, including the Clemson Tigers‘ much-hyped showdown vs. the LSU Tigers in Memorial Stadium.
Veteran college football insider Brett McMurphy reported Tuesday that Clemson and LSU will kick off in prime time at 7:30 p.m. ET from Memorial Stadium. The game will be televised on ABC.
Earlier that day, Syracuse will face the Tennessee Volunteers at Mercedes-Benz Stadium in Atlanta at noon ET. The game will be televised on ABC. At 3:30 p.m. ET, the Florida State Seminoles will host the Alabama Crimson Tide at Doak Campbell Stadium in Tallahassee. That game will also be televised on ABC, McMurphy reported.
Virginia Tech and South Carolina are scheduled to meet Sunday at 3 p.m. ET at Mercedes-Benz Stadium on ESPN.
For Clemson and LSU, it will be their first head-to-head meeting since the College Football Playoff National Championship Game on Jan. 13, 2020. LSU and Heisman Trophy winner Joe Burrow capped a 15-0 season by beating Dabo Swinney’s Tigers, 42-25, at the Superdome in New Orleans.
This year’s meeting between Clemson and LSU will be the fifth all-time between the two schools. LSU leads the series, 3-1, with Clemson’s only victory coming in the 2012 Peach Bowl, a 25-24 upset on New Year’s Eve in Atlanta.
LSU will be making its first trip to Memorial Stadium this season, with Clemson set to make its first visit to Tiger Stadium in Baton Rouge to open the 2026 college football season.
Clemson went 10-4 a season ago, beating the SMU Mustangs 34-31 on a 56-yard Nolan Hauser game-winning field goal as time expired in the ACC Championship Game. The Tigers lost to the Texas Longhorns, 38-24, in the first round of the 2025 College Football Playoffs in Austin.
LSU is coming off a 9-4 season in Brian Kelly’s third year in Baton Rouge. LSU ended its season with a 44-31 win over Baylor in the Texas Bowl on New Year’s Eve.
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