Who makes 2025 women’s Final Four? Our latest March Madness picks and predictions

As the 2025 women’s NCAA Tournament enters the second weekend, it’s time to reset our Final Four picks after action-packed first and second rounds.

All four No. 1 seeds are still in it to win it, but USC suffered a major blow on Monday when superstar guard JuJu Watkins went down with a season-ending knee injury in a second-round game against Mississippi State. The Trojans still stomped to a big win behind Kiki Iriafen and her 36 points, but they are on a collision course with Paige Bueckers and UConn in the Elite Eight with room for only one in the Final Four.

So, here are Final Four predictions from reporters across the USA TODAY Sports Network.

Women’s Final Four picks

• Nancy Armour, USA TODAY: UCLA, UConn, Texas, Duke 
• Cora Hall, Knoxville News Sentinel: South Carolina, UConn, NC State, Notre Dame  
• Meghan Hall, For The Win: UCLA, UConn, Notre Dame, South Carolina 
• Mike Sykes, For The Win: NC State, UConn, South Carolina, Texas  
• Lulu Kesin, Greenville News: South Carolina, UConn, LSU, Texas  
• Jenna Ortiz, Arizona Republic: South Carolina, UConn, UCLA, TCU 
• Cydney Henderson, USA TODAY: UCLA, UConn, South Carolina, TCU  
• Jordan Mendoza, USA TODAY: UCLA, USC, South Carolina, Notre Dame   
• Cory Diaz, Lafayette Advertiser: UCLA, UConn, South Carolina, Notre Dame 
• Maxwell Donaldson, The Gadsden Times: LSU, UConn, South Carolina, TCU 

Who will win Women’s March Madness?

Here are national championship predictions from our experts.

• Cydney Henderson, USA TODAY: South Carolina over UCLA 
• Cora Hall, Knoxville News Sentinel: South Carolina over UConn 
• Lulu Kesin, Greenville News: South Carolina over UConn 
• Meghan Hall, For The Win: South Carolina over UConn 
• Mike Sykes, For The Win: UConn over South Carolina 
• Cory Diaz, Lafayette Advertiser: UConn over South Carolina 
• Maxwell Donaldson, The Gadsden Times: UConn over South Carolina 

When is women’s Final Four?

The Final Four of the 2025 women’s NCAA Tournament is Friday, April 4 with the first game tipping off at 7 p.m. and the second game followng 30 minutes after the first game ends.

Where is women’s Final Four?

The Final Four is in Tampa, Fla., at Amalie Arena.

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